Paul Coppo Selected Research

Plasma Exchange

1/2020	Refractory Auto-Immune Thrombotic Thrombocytopenic Pupura Successfully Treated With Caplacizumab.
12/2019	Amotosalen-inactivated fresh frozen plasma is comparable to solvent-detergent inactivated plasma to treat thrombotic thrombocytopenic purpura.
11/2019	Therapeutic plasma exchange in thrombotic thrombocytopenic purpura.
1/2019	Developments in the use of plasma exchange and adjunctive therapies to treat immune-mediated thrombotic thrombocytopenic purpura.
10/2018	Plasma Exchanges for Refractory Evans Syndrome.
2/2017	Treatment of autoimmune thrombotic thrombocytopenic purpura in the more severe forms.
9/2016	Efficacy of rituximab and plasmapharesis in an adult patient with antifactor H autoantibody-associated hemolytic uremic syndrome: A case report and literature review.
8/2016	Twice-daily therapeutical plasma exchange-based salvage therapy in severe autoimmune thrombotic thrombocytopenic purpura: the French TMA Reference Center experience.
11/2015	Rituximab in autoimmune thrombotic thrombocytopenic purpura: A success story.
10/2015	Type of plasma preparation used for plasma exchange and clinical outcome of adult patients with acquired idiopathic thrombotic thrombocytopenic purpura: a French retrospective multicenter cohort study.

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Paul Coppo Research Topics

Disease

75	Thrombotic Thrombocytopenic Purpura 03/2022 - 05/2002
35	Thrombotic Microangiopathies 05/2022 - 10/2002
16	acquired Thrombotic thrombocytopenic purpura 01/2021 - 03/2010
13	Thrombocytopenia (Thrombopenia) 01/2020 - 01/2009
12	Neoplasms (Cancer) 01/2019 - 05/2002
10	Hemolytic Anemia 01/2020 - 12/2006
8	Hemolytic-Uremic Syndrome 05/2022 - 05/2002
8	Infections 10/2018 - 05/2002
6	Cytopenia 01/2021 - 11/2004
6	Lymphoma (Lymphomas) 01/2021 - 01/2014
6	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 12/2006
5	Acute Kidney Injury (Acute Renal Failure) 01/2021 - 02/2008
4	Thrombosis (Thrombus) 01/2022 - 01/2003
4	Hemolysis 01/2021 - 01/2014
4	Ischemia 01/2019 - 01/2009
3	Hypertension (High Blood Pressure) 05/2022 - 01/2019
3	Hemorrhage 01/2020 - 07/2015
3	Anemia 06/2019 - 09/2016
3	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 11/2014 - 05/2008
3	Renal Insufficiency (Renal Failure) 01/2014 - 02/2008
3	HIV Infections (HIV Infection) 03/2012 - 07/2004
2	Atypical Hemolytic Uremic Syndrome 05/2022 - 11/2020
2	Proteinuria 02/2022 - 01/2022
2	Purpura 01/2022 - 11/2018
2	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 04/2021 - 02/2010
2	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 11/2020 - 11/2018
2	Disease Progression 01/2020 - 01/2012
2	Neurologic Manifestations (Neurological Manifestations) 01/2020 - 07/2004
2	Stroke (Strokes) 06/2019 - 10/2018
2	Hematologic Neoplasms (Hematological Malignancy) 09/2014 - 11/2004
2	Sepsis (Septicemia) 09/2014 - 04/2007
2	Neutropenia 03/2013 - 11/2004
2	Connective Tissue Diseases (Connective Tissue Disease) 03/2012 - 05/2002
2	Diarrhea 03/2009 - 05/2002
1	Immunoglobulin G4-Related Disease 03/2022
1	Chronic Kidney Failure (Chronic Renal Failure) 11/2021
1	Large Granular Lymphocytic Leukemia 10/2021
1	Sickle Cell Anemia (Hemoglobin S Disease) 01/2021
1	Breast Neoplasms (Breast Cancer) 01/2021
1	Pre-Eclampsia (Preeclampsia) 11/2020
1	Eclampsia 11/2020
1	Inflammation (Inflammations) 10/2020
1	Epistaxis (Nosebleed) 01/2020
1	Brain Diseases (Brain Disorder) 01/2020

Drug/Important Bio-Agent (IBA)

50	thiamine triphosphorate (TTP)IBA 02/2022 - 05/2002
17	Rituximab (Mabthera)FDA Link 01/2021 - 03/2010
15	AutoantibodiesIBA 11/2021 - 11/2004
11	DisintegrinsIBA 01/2021 - 01/2009
11	Metalloproteases (Metalloproteinases)IBA 01/2021 - 01/2009
10	von Willebrand FactorIBA 11/2021 - 01/2009
10	ThrombospondinsIBA 01/2021 - 01/2009
8	caplacizumabIBA 03/2022 - 01/2019
7	AntibodiesIBA 11/2020 - 07/2004
6	ADAMTS13 ProteinIBA 01/2021 - 01/2009
6	EnzymesIBA 11/2020 - 03/2009
6	Cyclophosphamide (Cytoxan)FDA LinkGeneric 11/2017 - 11/2004
5	Biological ProductsIBA 03/2022 - 08/2009
5	Immunoglobulin G (IgG)IBA 03/2022 - 01/2014
5	eculizumab FDA Link 01/2021 - 04/2013
4	Shiga Toxin (Shigella Toxin)IBA 05/2022 - 05/2002
4	Etoposide (VP 16)FDA LinkGeneric 04/2021 - 05/2013
4	SteroidsIBA 01/2020 - 11/2004
4	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2015 - 06/2010
4	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2015 - 06/2010
4	Ferritins (Ferritin)IBA 11/2014 - 05/2008
3	Gemcitabine FDA Link 01/2021 - 01/2019
3	AntigensIBA 01/2020 - 03/2013
3	Antinuclear AntibodiesIBA 04/2017 - 07/2004
2	CreatinineIBA 01/2022 - 11/2021
2	HLA Antigens (Human Leukocyte Antigens)IBA 01/2022 - 01/2018
2	Complement System Proteins (Complement)IBA 11/2020 - 03/2009
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2020
2	Hemoglobins (Hemoglobin)IBA 12/2019 - 11/2014
2	Triglycerides (Triacylglycerol)IBA 11/2014 - 09/2014
2	Fibrinogen (Factor I)FDA Link 09/2014 - 03/2009
2	Monoclonal AntibodiesIBA 01/2014 - 03/2009
2	Hemostatics (Antihemorrhagics)IBA 02/2013 - 03/2009
2	Complement Factor H (Factor H)IBA 03/2009 - 03/2004
2	Pharmaceutical PreparationsIBA 02/2008 - 11/2004
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	ruxolitinibIBA 10/2021
1	Ifosfamide FDA LinkGeneric 04/2021
1	Brentuximab VedotinIBA 04/2021
1	Carboplatin (JM8)FDA LinkGeneric 04/2021
1	HaptoglobinsIBA 01/2021
1	Bevacizumab (Avastin)FDA Link 01/2021
1	EpitopesIBA 11/2020
1	HLA-DRB1 Chains (HLA DRB1)IBA 10/2020
1	Lenalidomide (CC 5013)FDA Link 01/2020

Therapy/Procedure

16	Plasma Exchange 01/2020 - 10/2002
14	Therapeutics 01/2022 - 02/2008
6	Drug Therapy (Chemotherapy) 01/2021 - 05/2002
4	Transplantation 01/2018 - 05/2002
3	Hematopoietic Stem Cell Transplantation 01/2017 - 03/2013
2	Catheters 01/2020 - 07/2015
2	Highly Active Antiretroviral Therapy (HAART) 12/2017 - 06/2010
2	Salvage Therapy 08/2016 - 11/2012
2	Platelet Transfusion (Blood Platelet Transfusions) 07/2015 - 06/2015
1	Critical Care (Surgical Intensive Care) 01/2021
1	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2021